Clomid for Thyroid Recovery !!!

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Clomid for Thyroid Recovery !!!

Clomid for Thyroid Recovery
by:Anthony Roberts

The question is: why didn't I go one step further, and move on to examining other, similar compounds? I should have, honestly- because then I might not have needed to have it pointed out to me. Clomid (Clomiphene Citrate) is used for a very similar purpose as HCG is (to augment fertility in women), so why can't we use it to help out our thyroid after prolonged use of thyroid hormones? Well, the answer -as you may have guessed from the title of this piece- is that we can!

Unfortunately, I lost track of the original study that was sent to me where Clomid was found to stimulate thyroid hormone production, but I managed to find quite a few on my own. Before we dive into that, a brief refresher course on the thyroid gland and the hormones involved in regulating thyroid function is probably in order.

First, lets find it…

After my article on using HCG to help repair the thyroid, I was asked to go on the radio with Carl Lanore and speak on that topic. Well, to make a long story short, I did go on the radio and I didn't end up speaking on that topic at all. What happened is that the host of the show called me, and we started discussing thyroid repair and related topics…and I ended up e-mailing him about five of my strongest articles, and he decided to take a different route with the interview. He eventually interviewed me on anabolic steroids and their various mechanisms of action, possible and impossible side effects, and the media hype surrounding them.

But in the course of my interaction with him, he ended up e-mailing me an abstract that was in-line with my original piece on thyroid repair. I'm actually kind of annoyed with myself for not figuring it out beforehand. If you recall, in that piece, I said: …that much of the thyroid's action is regulated by the pituitary, and looking at compounds that could operate in that nexus of effects, I found HCG…but…even though my logic seemed sound (funny how it always does to me), I wanted to be 100% sure about this. That's when I ended up taking a close molecular look at HCG... (1)

The question is: why didn't I go one step further, and move on to examining other, similar compounds? I should have, honestly- because then I might not have needed to have it pointed out to me. Clomid (Clomiphene Citrate) is used for a very similar purpose as HCG is (to augment fertility in women), so why can't we use it to help out our thyroid after prolonged use of thyroid hormones? Well, the answer -as you may have guessed from the title of this piece- is that we can! Unfortunately, I lost track of the original study that was sent to me where Clomid was found to stimulate thyroid hormone production, but I managed to find quite a few on my own. Before we dive into that, a brief refresher course on the thyroid gland and the hormones involved in regulating thyroid function is probably in order.

First, lets find it…

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Take your hands, and feel around, in front of your neck. If you're a man, you can use your Adam's apple as a point of reference. Your thyroid is just below that, and above the top edge of your breastbone. If you're a woman and you are using your Adams apple as a point of reference, then your career in professional bodybuilding has apparently taken its toll on you.

Anyway, the thyroid gland is made up of two lobes (one on the right and one on the left). These lobes are connected by a narrow band in the middle, called the isthmus. From the isthmus, a thin band of tissue called the pyramidal lobe extends upward. If you use your imagination, it looks kind of like a butterfly with the left and right lobes being the two “wings.” Alternately, it just looks like a very detailed Rorschack blot to you. Anyway, the thyroid gland partially wraps around your voice box (larynx) and windpipe (trachea), both of which are found right by where your hand was a second ago (you can put your hands down now). The “wings” of our thyroid butterfly are kind of snuggled in behind your neck muscles, at the top of your breast bone (2).

Now that we're on the same page concerning the location of the thyroid gland, here's what it does: the thyroid gland secretes thyroxine (typically referred to as T4) and triiodothyronine (typically referred to as T3). T3 is the “active” hormone, with T4 being converted into T3 by an enzyme called deiodinase; about 80% of your T3 comes from T4 being converted by this enzyme. T4 secretion is regulated by Thyroid Stimulating Hormone (TSH), which is produced by the pituitary gland. TSH is, itself, controlled primarily through release of Thyrotropin Releasing Hormone (TRH), which is produced in your hypothalamus (2).

So how does Clomid fit into this picture? And how can we use it as part of our thyroid PCT?

Well, in one study I looked at, the researchers concluded that it is evident from their investigation into the matter that Clomid must either act via the hypothalamus or directly over the pituitary to increase TSH secretion, which of course is then followed by increased thyroid activity (3). Sounds promising for us, if are looking for a drug to aid in a speedy recovery of normal thyroid function after prolonged use of thyroid hormones. In fact, in some cases, Clomid is actually used in conjunction with thyroid replacement for the treatment of a luteal-phase defect in patients with subclinical hypothyroxinemia (4).

I do need, however, to state at this point that this will probably be a much more effective therapy for thyroid repair in women than it will in men, as was the case when I introduced HCG for this purpose. In women, body temperature is one of the indicators for ovulation and the various stages of the menstrual cycle. This is because a specific temperature range in a woman's BBT (Basal Body Temperature) is required for successful reproduction.

All of this means that HCG is therefore going to be much more effective at repairing a woman's thyroid then a man's, simply because their bodies are much more sensitive to the compounds we're discussing here. Does that mean that this method won't work for men as well as women? Certainly not. As was the case with HCG, both of these compounds will work to repair the thyroid - specifically, by increasing TRH output and stimulating thyroidal activity. And, as was the case with HCG, I can support my claim that it works for men as well as women. In the final study I looked at, 100 mg of Clomid was given once a day to two groups of healthy male volunteers for either 5 or 12 straight days, respectively. In the 5-day group, on day 5, a slight increase in TSH was observed, although before that, there was a slight decrease. In the 12-day group, the response of TSH to TRH showed a slight (non-significant) increase after 5 days and a significant increase after 12 days on Clomid. The researchers concluded that the observed results indicate that Clomid exerts an [(in my eyes) stimulatory] influence directly on thyroid function (5). But, keep in mind that the effects didn't even start until day five, and increased as Clomid therapy continued. I'd therefore recommend 100mgs/day of Clomid for a minimum of 12 days, and even up to three to four weeks at that dose, to speed up thyroid recovery.

So there you have it, an unplanned part two to my article on using HCG to repair your thyroid. Clomid at 100mgs/day in either males or females should help get thyroid function recovered as quickly as possible.
 
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